Tuesday, June 03, 2014

Yet more bacteria found where they weren't expected

Gee, it seems like every week there's a story about bacteria being found in parts of the body where they weren't expected.  (It was the placenta last week.)

This week - it's the healthy male urogenital tract:
Much like the vaginal microbiome differs among women and changes over time, the penis is home to a variety of bacteria that vary with a man’s age, sexual activities, and whether he is circumcised, among other things. And it’s not just the skin that envelops the male sexual organ that’s inhabited by microbes: researchers continue to identify bacteria that dwell within the urogenital tract, a site once considered sterile in the absence of infection.

David Nelson, an associate professor of microbiology and immunology at Indiana University in Bloomington, was investigating Chlamydia infections when he and his colleagues found evidence to suggest that the sexually transmitted pathogens in the urogenital tract were obtaining metabolites from other microbes. “There was a signature in the chlamydial genome that suggested this organism might be interacting with other microorganisms,” said Nelson. “That’s what initially piqued our interest. And when we went in and started to look, we found that there were a lot more [microbes] than we would have anticipated being there.”

The researchers found that some men pass urine containing a variety of lactobacilli and streptococci species, whereas others have more anaerobes, like Prevotella and Fusobacterium. In terms of overall composition, “we see a lot of parallels to the gut,” said Nelson, noting that there doesn’t seem to be a standout formula for a “healthy” urogenital tract. Commensal microbes within the urethra could make a man more susceptible to infection by supporting colonization by pathogens like Chlamydia, whereas bacteria that consume the environment’s nutrients could help prevent it. “We just don’t know at this point,” said Nelson.
I would presume that men who partake of a particular activity without condoms might generally have a larger number of bacteria to be found there, for obvious reasons

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