Brain scan scepticism

Ukraine and war and right wing nuttiness (along with the occasional bit of left wing nuttiness*) has been crowding out other interesting stuff lately, but here's an article at Nature of note, about a field of research that seems to have been making dubious connections:

Now, in a bombshell 16 March Nature study¹, Marek and his colleagues show that even large brain-imaging studies, such as his, are still too small to reliably detect most links between brain function and behaviour.

As a result, the conclusions of most published ‘brain-wide association studies’ — typically involving dozens to hundreds of participants — might be wrong. Such studies link variations in brain structure and activity to differences in cognitive ability, mental health and other behavioural traits. For instance, numerous studies have identified brain anatomy or activity patterns that, the studies say, can distinguish people who have been diagnosed with depression from those who have not. Studies also often seek biomarkers for behavioural traits.

“There’s a lot of investigators who have committed their careers to doing the kind of science that this paper says is basically junk,” says Russell Poldrack, a cognitive neuroscientist at Stanford University in California, who was one of the paper’s peer reviewers. “It really forces a rethink.”

 

*   I saw that trans swimmer Lia Thomas talking for the first time on the weekend and I am completely unsurprised that most Americans probably think it's a nonsense that he is allowed to blitz the women's competition.  What gets up my nose is a decent trans person would recognise and accept the unfairness.  It may be that Right wingers lack nuance on the issue, but so do Lefties who refuse to acknowledge the unfairness and think trans can never be not allowed to do something in their elected gender.