This article gives a pretty comprehensive coverage of the never ending quest to find a decent male contraceptive. I was most impressed with this line, though:
Compared with the one-egg-per-month output of the female reproductive system, the roughly 1,000-sperm-per-heartbeat output of the male reproductive system is "a quantitatively challenging problem" for contraceptive research, Amory says.Young single men: feel free to incorporate this factoid during your next venture in a singles bar. Married men: impress your wife by offering this new found knowledge during a dinner party with that nice new couple you recently met.
There's one other quote that I thought interesting from the article:
In animal models the compound bisdichloroacetyldiamine safely and reversibly induces infertility by inhibiting an enzyme, aldehyde dehydrogenase 1a2, required for retinoic acid synthesis in the testes. Unfortunately, bisdichloroacetyldiamine also inhibits a similar enzyme, aldehyde dehydrogenase 2, required for alcohol metabolism in the liver—meaning that animals on bisdichloroacetyldiamine were unable to process alcohol. "And some would say that if it weren't for alcohol no one would need a contraceptive anyway," jokes AmoryWhat happens if you "can't process alcohol"? Would five drinks keep you drunk for a week? (I guess it takes a while to for it to get out of you via the lungs.) Would 12 drinks in a day pickle your insides?
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