Thursday, September 18, 2014

Those gut bugs messing with our plans, again

Sugar substitutes linked to obesity
A team led by Eran Elinav of the Weizmann Institute of Science in
Rehovot, Israel, fed mice various sweeteners — saccharin, sucralose and
aspartame — and found that after 11 weeks, the animals displayed glucose
intolerance, a marker of propensity for metabolic disorders.

To simulate the real-world situation of people with varying risks of these
diseases, the team fed some mice a normal diet, and some a high-fat
diet, and spiked their water either with glucose alone, or with glucose
and one of the sweeteners, saccharin. The mice fed saccharin developed a
marked glucose intolerance compared to those fed only glucose. But when
the animals were given antibiotics to kill their gut bacteria, glucose
intolerance was prevented. And when the researchers transplanted faeces
from the glucose-intolerant saccharin-fed mice into the guts of mice
bred to have sterile intestines, those mice also became glucose
intolerant, indicating that saccharin was causing the microbiome to
become unhealthy.

7 comments:

  1. There is also some worrying data on aspartame. It is not safe, should be avoided.

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  2. Really? Should I worry about a can of Pepsi Max about 5 days a week?

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  3. Nah, it is about the frequency of use Steve. Many people have 3-4 cans of sodas a day that is a huge problem. We have to wean ourselves off the taste of sugar. It takes time but it does happen. A friend and myself have been data mining on the impact of sugar on metabolism. It is just plain bad and needs to avoided. A recent study highlighted that sugar is the primary and only significant cause of tooth decay.

    While I don't particularly like the idea of regulating sugar intake an analysis released today shows that in the USA the obesity rates are still climbing. We are now at a point where obesity associated pathologies are adding huge costs to health budgets and we are going to have to start forcing corporations and\or individuals to recognise that the excess sugar loading is just as bad as smoking; if not worse. So where's that spontaneous order now?

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  4. I see Mexico often features these days as very, very high on the list of countries sugar is enlarging.

    I like a little bit of sweetness in coffee or tea, but I've taken to using one of the stevia based sweeteners for that. I hope it remains in the clear...

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  5. I thought you wrote Pepsi Max once every 5 days. I won't go anywhere near aspartame. Here's one reason why

    http://www.nature.com/ejcn/journal/v63/n8/full/ejcn200838a.html

    Another((there are studies also highlighting the induction of brain inflammation)
    The Secret History of the War on Cancer
    422
    Aspartame
    U..S Air Force magazine, Flying Safely and the US Navy Magazine Navy Physiology warned that aspartame can cause serious brain problems in pilots.
    Circa 1995 FDA stopped gathering adverse reports.
    423
    ALL studies promoting the safety of aspartame were industry sponsored. Every single study questioning its safety was by non-industry scientists.
    424
    Sprague-Dawley rats: ate aspartame from birth to death. Dose related increases in lymphomas leukemias and tumours of the renal pelvic area and other cancers.

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  6. Steve's a moron12:30 am

    Does Monty, the pretend husband, know this. He'll have to cut it back to 100 or so doughnuts an hour.

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