ScienceDaily: Ever-happy Mice May Hold Key To New Treatment Of Depression
Interesting story on genetic manipulation leading to very happy mice.
As usual, I wonder about this:
Mice without the TREK-1 gene ('knock-out' mice) were created and bred in collaboration with Dr. Michel Lazdunski, co-author of the research, in his laboratory at the University of Nice, France. "These 'knock-out' mice were then tested using separate behavioral, electrophysiological and biochemical measures known to gauge 'depression' in animals," says Dr. Debonnel. "The results really surprised us; our 'knock-out' mice acted as if they had been treated with antidepressants for at least three weeks."
Just how closely does depression in a mouse represent depression in a human?
Anyway, apart from the drug development implications, it does raise the question as to whether "designer babies" in the future could be tailored to never suffer depression. What unknown effects would this have on personality or culture if it ever became widespread? Just wondering.
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