Tuesday, April 08, 2008

Screen your genes before lighting up?

Genetics and lung cancer | Smoking out the smoking gene | Economist.com

I'll step on Harry Clarke's territory now and link to an interesting article about genes and lung cancer. Two paragraphs give you the flavour:

Paul Brennan and Christopher Amos both agree that something significant is going on in the part of chromosome 15 studied by deCODE. But they have concluded that genetic variation there acts directly on a person's susceptibility to lung cancer, rather than acting indirectly by modifying his smoking behaviour. That does not mean the gene or genes in question actually cause lung cancer. Rather, it means that they amplify the effects of smoking instead of the amount of smoking....

DeCODE has already announced it will add rs1051730 to the standard screen it offers to those who wish to know their susceptibility to diseases. The day is not far off, therefore, when those who take the essentially irrational decision to start smoking tobacco will be able to find out in advance exactly how foolish they are being.

The Scientific American version of the story is here.

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