Here's a rather fascinating story from medical history: for a couple of decades in the first half of the 20th century, deliberately infecting poor sufferers of neurosyphilis with malaria was actually a reputable and (it seems) pretty widespread treatment. The fever seemed to help quite a few recover enough to leave asylums, although that article notes that there was little in the way of detailed follow up.
And the problem of neurosyphilis was a major one:
Many patients were involuntarily institutionalized in epidemic numbers:
in the early 20th century, neurosyphilis was responsible for 5 to 10% of
all psychiatric admissions.
I don't think I have ever heard of this treatment before.
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