Sunday, July 07, 2019

When "the hair of the dog" might really save you..

A report from a Filipino news site talks about recent poisoning there from people drinking cheap gin, probably due to methanol content.  Actually, Googling the topic, I see that 6 people died in Penang recently from it (19 sickened in Malaysia in a recent period), and I think it's still suspected in the recent Dominican Republic tourist deaths.  So, it's a pretty topical subject.

Anyway, the Filipino story explains how this tasteless alcohol works:
Lim said naturally produced methanol is safe. It only becomes poisonous when it is ingested and converted into formic acid and formate in the body.

When mixed with ethanol, methanol doesn’t immediately metabolize. However, Lim explained that ethanol exits the body through exhalation, leaving methanol in the body to break down.

“You wait a bit of time for (methanol) to break down to formic. In our studies, it takes a minimum of 6 hours,” she said.

The formic acid will then seep into the bloodstream and spread throughout the body. “It is very acidic and it damages the eyes,” Lim said.

OK.  Here's the part that surprised me (my bold):
While initial symptoms are similar to regular alcohol intoxication, Lim said people should be alarmed when they are still experiencing a severe hangover after 12 hours.

“If after 12 hours you are still not feeling well . . . You are vomiting, you feel weak and your head hurts, you need to consult a doctor,” she said.

While it may sound counterintuitive, Lim said taking gin or other hard drinks will help a victim if it will take time to reach a hospital, because ethanol contained in those drinks will help slow the breakdown of methanol.

“Even if you’re not sure if the drink has been contaminated with methanol . . . It’s still going to be an antidote (because it has ethanol),” she said.

At the hospital, methanol poisoning patients are then given more ethanol, a bicarbonate to buffer the acidosis then folic acid to convert the toxic formate into carbon dioxide and water.

“But it’s dialysis that will really remove the methanol from your body,” Lim said.
There you go.  I might have saved a reader's life.  Either that or ended a marriage when some spouse thinks their partner is definitely a chronic alcoholic for drinking when really sick with a hangover...

1 comment:

GMB said...
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