Friday, April 16, 2021

Why did it have to be... clots in the brain?

Just a random Friday thought for you:   a large part of the PR problem for the AstraZeneca and now Johnson & Johnson vaccines is (I reckon) that the exceeding rare but very dangerous side effect is one that sounds like a particularly nasty way to die:

In another hiccup [you don't say?] for AstraZeneca’s COVID-19 vaccine, data suggest it is in fact linked to blood clots that have formed in the brains of some vaccinated people, the European Medicines Agency announced April 7....

The EMA had previously concluded that the vaccine, developed by AstraZeneca and the University of Oxford, was not linked to blood clots overall (SN: 3/18/21). But experts were uncertain about 18 case reports of blood clots in the sinuses that drain blood from the brain, a rare condition called cerebral venous sinus thrombosis or CVST...

As of March 22, countries had reported 62 cases of CVST out of around 25 million people who got the AstraZeneca vaccine. There were also 24 reported cases of clots in veins that drain blood from the digestive system, called splanchnic vein thrombosis or SVT. Eighteen of the people with CVST or SVT died. 

It's only human to have risk assessment affected by the imagination of what it would be like to die from the particular danger.   I mean, do we really blame people for breaking out in a sweat if they hear someone yell "shark" at the surf beach while their kids are out in the waves, even though they will stand a million times bigger chance of dying in a car accident on the way home? 

And I mean, while I know a stroke is, basically, often just a single blockage in the brain, the idea that could develop several clots at once sounds very dire and, um, icky?

It's also the fact that the clotting problem arises (so it seems) a few days after the injection.   People are, I imagine, now going to be hypersensitive to headaches and stomach cramps post vaccination.   If it were a case of some people dying within, say, an hour due to immediate reaction, you could at least have people hanging around the clinic until the danger period is over. 

This is all very unfortunate, but people really hate the idea of dying accidentally from something meant to prevent death.

I haven't decided what I would do if told the AstraZeneca is available next month:  call me unscientific, if you want, but if I'm not planning on heading overseas soon, I would just as soon wait until the vaccine which does not cause clots in the brain is available.

Update:   speaking of serious blood clotting - I seemed to recall that was the way the outer space  bug in The Andromeda Strain killed people.  I was right:

The Wildfire team, led by Dr. Jeremy Stone, believes the satellite—intentionally designed to capture upper-atmosphere microorganisms for bio-weapon exploitation—returned with a deadly microorganism that kills through nearly instantaneous blood clotting

Maybe my unreasonable fear of death by massive blood clot can be put on Michael Crichton.

1 comment:

TimT said...

Maybe it would be safer to catch COVID oh wait.


https://www.cidrap.umn.edu/news-perspective/2021/04/study-covid-much-more-likely-vaccines-cause-blood-clots