Tuesday, May 18, 2021

Reason to live in high income country

New Scientist reported recently:

Piping an oxygen-rich liquid through the anus could be a life-saver. A new treatment for failing lungs that involves such a process has been successfully tested in pigs....

The researchers anaesthetised four pigs and put them on a ventilator that gave them a lower breathing rate than normal, so their blood oxygen levels fell. When they gave two of the pigs enemas of the oxygenated fluid, replaced once an hour, their blood oxygen levels rose significantly after each infusion. The same effect happened when the fluid was delivered by a tube surgically inserted into the rectums of the other two pigs.

If there is a similar-sized effect in people, it would be enough to provide a medical benefit, says Takebe. He thinks the approach could be especially useful in low-income countries that have fewer intensive care facilities. “Ventilators are super-expensive and need a number of medical staff to manage,” he says. “This is just a simple enema.”

One problem is that gut function may be impaired in people sick enough to need intensive care, which can cause diarrhoea, says Stephen Brett at Imperial College London. “It’s too early to say if this has got any legs,” he says.

Yes, interesting point about the enema aspect.  I wouldn't know for sure, but I didn't think it took all that much liquid insertion via enema for the intestines to want to shoot it out again.   How's that supposed to be stopped?

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