Wednesday, October 04, 2023

An encouraging story

I hadn't noticed that there are some (not perfect, but pretty good) vaccines for malaria being deployed now.

As NPR reports, the disease is ridiculously widespread in parts of Africa:

For example, in Burkina Faso in West Africa, pretty much everyone gets malaria. Last year, out of a population of 20-some million, about half got sick. Halidou Tinto was one of them. He leads the Clinical Research Unit of Nanaro in the country. His six-year-old twins also fell ill with malaria this year.

"As soon as [the children] are febrile or they complain about headache," Tinto says, "you have to think about malaria and treat them immediately. And you can avoid any bad outcome of the disease."

The worst outcome is death. Tinto says 4,000 people died of malaria last year in Burkina Faso alone. In 2021, across Africa, it's estimated that 619,000 died of the mosquito-borne disease, most of them children.

"People are living with the disease," says Tinto. "But of course, we are not happy and we are not proud of this."

But on the "up" side:

They're the first vaccines designed to work against a human parasite.

The first, called RTS,S, was unveiled almost two years ago. The second one, recommended by the World Health Organization this week, is called R21/Matrix-M and is intended for children between 5 and 36 months, who are among the most vulnerable to the disease....

This is what makes WHO's approval of the second malaria vaccine such welcome news. Tinto ran the clinical trials in Burkina Faso that led to its recommendation. Across four African countries, these trials showed a 75% reduction in malaria cases in the year following vaccination of young children.

"I am very, very happy," says Tinto, "and we are pretty sure this vaccine will have a big impact in term[s] of public health."

 

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