Case studies and autopsy results are confirming that, in some cases, COVID-19 can cause such severe lung damage that patients require a lung transplant to survive. ....
"We provide explicit evidence that COVID-19 can cause permanent damage to the lung in some patients for whom lung transplantation is the only hope for survival," said study principal investigator Dr. Ankit Bharat. He's chief of thoracic surgery and surgical director of the Northwestern Medicine Lung Transplant Program, in Chicago.
His team also discovered unique cells—called KRT17 epithelial cells—in the lung tissue of COVID-19 patients with irreversible damage. These cells have also been found in patients with end-stage pulmonary fibrosis, a deadly progressive lung disease.
The findings, the first of their kind on the issue, were published Nov. 30 in Science Translational Medicine. To date, eight COVID-19 patients have received double-lung transplants at Northwestern Medicine, the most performed at any health system in the world.
Pretty extraordinary (and not widely publicised, it seems.)







