More on cat germs and schizophrenia

Scientists Find Unusual Immune System Activity in Brains of Schizophrenics

....researchers in Sweden and Germany found that recent-onset schizophrenics-- those first showing symptoms, usually young adults-- had elevated amounts of interleukin-1beta in their spinal fluid. In normal controls, IL-1beta levels were nearly undetectable.

The researchers looked at around 10 common cytokines, proteins used by the body's defenses to communicate with immune cells, but only IL-1beta was unusually expressed in the mentally ill patients. ...

As early as the 1970s, some scientists have suggested that schizophrenia, which afflicts about 1 percent of the U.S. population, could be triggered by an infection.

A popular candidate has been the protozoan Toxoplasma gondii, transmitted from cat feces or uncooked meats. Engberg says infection from the toxoplasma parasite more than doubles one's risk for schizophrenia. "Toxoplasma gondii appears to be one of several micro-organisms that can trigger [the] brain immune system," he says.