Monday, July 29, 2019

Planet of the Rats

Japan is going to do some human stem cell in animal experiments that sound a little confusing:
A Japanese stem-cell scientist is the first to receive government support to create animal embryos that contain human cells and transplant them into surrogate animals since a ban on the practice was overturned earlier this year.

Hiromitsu Nakauchi, who leads teams at the University of Tokyo and Stanford University in California, plans to grow human cells in mouse and rat embryos and then transplant those embryos into surrogate animals. Nakauchi's ultimate goal is to produce animals with organs made of human cells that can, eventually, be transplanted into people....

Nakauchi says he plans to proceed slowly, and will not attempt to bring any hybrid embryos to term for some time. Initially, he plans to grow hybrid mouse embryos until 14.5 days, when the animal’s organs are mostly formed and it is almost to term. He will do the same experiments in rats, growing the hybrids to near term, about 15.5 days. Later, Nakauchi plans to apply for government approval to grow hybrid embryos in pigs for up to 70 days.

The reason why some people worry about these experiments:
Some bioethicists are concerned about the possibility that human cells might stray beyond development of the targeted organ, travel to the developing animal’s brain and potentially affect its cognition.
Oh.

1 comment:

GMB said...

Seldom do these people do anything useful with this technology. Its usually The Island of Doctor Moreau, all over again.