Thursday, August 05, 2021

In rodent news..

Over at Science Daily there are some rodent studies of interest:

Rats prefer to help their own kind; Humans may be similarly wired

The findings, published today, Tuesday, July 13, in the journal eLife, suggest that altruism, whether in rodents or humans, is motivated by social bonding and familiarity rather than sympathy or guilt.

"We have found that the group identity of the distressed rat dramatically influences the neural response and decision to help, revealing the biological mechanism of ingroup bias," said study senior author Daniela Kaufer, a professor of neuroscience and integrative biology at UC Berkeley.

With nativism and conflicts between religious, ethnic and racial groups on the rise globally, the results suggest that social integration, rather than segregation, may boost cooperation among humans.

"Priming a common group membership may be a more powerful driver for inducing pro-social motivation than increasing empathy," said study lead author Inbal Ben-Ami Bartal, an assistant professor of psychobiology at Tel-Aviv University in Israel.

I wonder - can this be cited as a reason urbanisation is more "civilising" than other ways humans can live?    Of course, as against that idea, I suppose that 20th fascism didn't exactly spring from the rural areas.   Maybe I am just trying too hard to find reasons why American wingnuttery is so centred in rural areas.

In another rodent article:

Researchers have discovered that spontaneous impulses of dopamine, the neurological messenger known as the brain's 'feel good' chemical, occur in the brain of mice. The study found that mice can willfully manipulate these random dopamine pulses for reward. 

This is all a bit confusing:

 Rather than only occurring when presented with pleasurable, or reward-based expectations, UC San Diego graduate student Conrad Foo led research that found that the neocortex in mice is flooded with unpredictable impulses of dopamine that occur approximately once per minute.

Working with colleagues at UC San Diego (Department of Physics and Section of Neurobiology) and the Icahn School of Medicine at Mount Sinai in New York, Foo investigated whether mice are in fact aware that these impulses -- documented in the lab through molecular and optical imaging techniques -- are actually occurring. The researchers devised a feedback scheme in which mice on a treadmill received a reward if they showed they were able to control the impromptu dopamine signals. Not only were mice aware of these dopamine impulses, the data revealed, but the results confirmed that they learned to anticipate and volitionally act upon a portion of them.

"Critically, mice learned to reliably elicit (dopamine) impulses prior to receiving a reward," the researchers note in the paper. "These effects reversed when the reward was removed. We posit that spontaneous dopamine impulses may serve as a salient cognitive event in behavioral planning."

 And finally, mouse eyes are sort of primed to know what to expect.  Makes sense, I guess:

A new Yale study suggests that, in a sense, mammals dream about the world they are about to experience before they are even born.

Writing in the July 23 issue of Science, a team led by Michael Crair, the William Ziegler III Professor of Neuroscience and professor of ophthalmology and visual science, describes waves of activity that emanate from the neonatal retina in mice before their eyes ever open.

This activity disappears soon after birth and is replaced by a more mature network of neural transmissions of visual stimuli to the brain, where information is further encoded and stored.

"At eye opening, mammals are capable of pretty sophisticated behavior," said Crair, senior author of the study, who is also vice provost for research at Yale." But how do the circuits form that allow us to perceive motion and navigate the world? It turns out we are born capable of many of these behaviors, at least in rudimentary form."

 

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